Idrabiotaparinux (natrium)

Idrabiotaparinux sodium is a derivative of Idraparinux synthesized with biotin. Idraparinux is a polymethylated synthetic pentasaccharide known to interact with the antithrombin III and act as anticoagulant[1][2].

405159-59-3

12352005

H302-H315-H319-H335

Thrombin

Metabolic Enzyme/Protease

Cardiovascular Disease

10 mM in DMSO

O=S(O[C@H]([C@H]([C@@H](O[C@@]1([H])[C@@H]([C@H]([C@H](O[C@@]2([H])[C@@H]([C@H]([C@@H](OC)O[C@@H]2COS(=O)(O[Na])=O)OS(=O)(O[Na])=O)OS(=O)(O[Na])=O)O[C@H]1C(O[Na])=O)OC)OC)O[C@@H]3COS(=O)(O[Na])=O)OS(=O)(O[Na])=O)[C@]3([H])O[C@H]4[C@@H]([C@H]([C@@](O[C@@H]5[C@@H]([C@H]([C@H](OC)[C@@H](COS(=O)(O[Na])=O)O5)OC)NC(CCCCCNC(CCCC[C@H]6[C@](N7)([H])[C@](NC7=O)([H])CS6)=O)=O)([H])[C@@H](C(O[Na])=O)O4)OC)OC)(O[Na])=O

C53H79N4Na9O51S8

2051.62

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

[1]Harenberg J. Development of idraparinux and idrabiotaparinux for anticoagulant therapy. Thromb Haemost. 2009;102 (5) :811-815. |[2]Paty I, Trellu M, Destors JM, Cortez P, Boëlle E, Sanderink G. Reversibility of the anti-FXa activity of idrabiotaparinux (biotinylated idraparinux) by intravenous avidin infusion. J Thromb Haemost. 2010;8 (4) :722-729.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-19442A/

Reference compound1

No Development Reported