IDUA Antilichaam / Alfa-L-iduronidase

IDUA encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans.

Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:50-1:100, Flow cytometry: 1:25 (1x10e6 cells)

P35475

Human

A portion of amino acids 236-264 from the human protein were used as the immunogen for the IDUA antibody.

WB, IHC-P, FACS

Antigen affinity purified

Purified

This IDUA antibody is available for research use only.

Aliquot the IDUA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

In 1X PBS, pH 7.4, with 0.09% sodium azide

The stated application concentrations are suggested starting points. Titration of the IDUA antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Cytoplasmic

Western blot testing of human 1) liver and 2) lung lysate with IDUA antibody. Expected molecular weight: 74-85 kDa.