Iduronaat 2 sulfatase (IDS) Mouse Monoclonal Antibody [Kloon ID: LBI1D9]

Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq]

Carrier-free (BSA/glycerol-free) IDS mouse monoclonal antibody, clone LBI1D9

MPS2; SIDS

Homo sapiens iduronate 2-sulfatase (IDS), transcript variant 1, mRNA.

3423

P22304

Unconjugated

Glycosaminoglycan degradation, Lysosome, Metabolic pathways

Glycosaminoglycan degradation, Lysosome, Metabolic pathways

WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

IDS

https://www.ncbi.nlm.nih.gov/gene/?term=3423

https://www.uniprot.org/uniprot/P22304