Ifebemtinib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1227948-82-4
IN-10018, BI-853520
FAK
Protein Tyrosine Kinase
C28H28F4N6O4
Ifebemtinib (IN10018, BI853520) is a highly selective, potent inhibitor of focal adhesion kinase (FAK), with an IC50 of 1 nM for inhibiting FAK autophosphorylation. It also inhibits FER Kinase and FES Kinase with IC50s of 900 nM and 1040 nM, respectively, inhibiting spheroid formation and orthotopic tumor growth in malignant pleural mesothelioma. IN10018 exhibits anti-tumor activity in vitro and in vivo.
Beschrijving
Ifebemtinib Beschikbaar in 1 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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