IFI16 (CT) Peptide

IFI16 Antibody: IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer. Increased expression of IFI16 predicts adverse prognosis in multiple myeloma. IFI16 isoforms with cytoplasmic and nuclear locations play differential roles in recognizing invaded DNA viruses. IFI16 directly senses viral RNA and enhances RIG-I transcription and activation to restrict influenza virus infection. Nuclear sensor IFI16 inhibits the function of Hepatitis B virus covalently closed circular DNA by integrating innate immune activation and epigenetic suppression.

3428

Q16666

Q16666.3

Peptides

200 ug/mL

PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

Blue Ice

Store ULBP1 peptide at -20˚ C, stable for one year.

IFI16 (CT) Peptide is used for blocking the activity of IFI16 (CT) Antibody.

Interferon gamma inducible protein 16

Homo sapiens

Ka et al. Cell Rep. 2021; 37 (12) :110138

Huang et al. Pharmacogenomics J. 2021; 21 (4) :520-532

Li et al. J Immunol. 2021; 207 (11) :2699-2709

Jiang et al. Nat Microbiol. 2021; 6 (7) :932-945

Yang et al. Hepatology 2020; 71 (4) :1154-1169

IFI16 Antibody: Gamma-interferon-inducible protein 16, Ifi-16, Interferon-inducible myeloid differentiation transcriptional activator, IFNGIP1

Blocking

Human

118572657

Liquid