IFI16 Polyklonale Antilichaam, Cy7 Vervoeging
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IFI16 Polyklonale Antilichaam, Cy7 Vervoeging

Catalog #: bs-1472R-Cy7-01
Maat: 20 µL

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Technische Documentatie

Technische Specificaties

Background

Interferon (IFN) Inducible 16 (IFI16) protein belongs to a family of HIN 200 human and mouse proteins. IFI16 is a nuclear protein comtaining regulatory domains such as DNA binding domain, transcriptional regulatory domain and DAPIN/PAAD domain. IFI16 has three isotypes A, B, and C (85-95 kDa), which arise as a result of mRNA alternative splicing. All are phosphorylated on serine and threonine residues and can homo and heterodimerize. Expression is restricted to the nuclei of hematopoietic cells, fibroblasts and epithelial cells. IFI16 expression in hematopoietic cells of myeloid lineage is tightly regulated and highly induced in the differentiation and proliferation of the cell. Due to its localization in the nucleus, regulation of protein expression, and ability to bind DNA, it is assumed that IFI16 has a role in transcription regulation of cell differentiation. In addition, it was found that IFI16 can act as a transcriptional repressor and is involved in regulation and activation of p53 in cancer cells.

Synonyms

Gamma-interferon-inducible protein i16; Interferon-inducible myeloid dferentiation transcriptional activator; A730048F03; D3; D3cDNA; i-d3; I16; I16B; I204; I205; i205a; i205b; NGIP1; MGC9466; Mnda; p204; PYHIN2.

Gene ID

3428

Cellular Locus

Cytoplasm, Nucleus

Host

• Rabbit

Cross Reactivity

Human

Immunogen

201-350/785

Target

IFI16

Clonality

• Polyclonal

Isotype

• IgG

Conjugation

Cy7

Source

KLH conjugated synthetic peptide derived from human IFI16

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

743nm/767nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3428

Beschrijving

IFI16 Polyklonale Antilichaam, Cy7 Vervoeging Beschikbaar in 20 µL. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamIFI16 Polyklonale Antilichaam, Cy7 Vervoeging
Categorie
Beschikbare grootte20 µL
Catalogusnummerbs-1472R-Cy7-01