IFIT1 Antilichaam

The interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) protein is a member of a family of tetratricopeptide repeat-containing proteins whose transcription is upregulated by interferons, virus infection, and molecular patterns such as dsRNA or lipopolysaccharides (1,2) . These proteins have been suggested to induce anti-viral cellular activities in response to infection (2) . Together with the interferon-induced transmembrane protein 1 (IFITM1), IFIT1 inhibits the replication of the Hepatitis C virus, suggesting that it may be useful in the development of therapeutic treatments (3) .

3434

P09914

NP_001539

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Innate Immunity

IFIT1 antibody is affinity chromatography purified via peptide column.

Cat. No. 1468 - Rat Small Intestine Tissue Lysate

1 mg/mL

IFIT1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

IFIT1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

IFIT1 antibody is human, mouse and rat reactive. At least three isoforms of IFIT1 are known to exist. This antibody is predicted to not cross-react with other members of the IFIT protein family.

IFIT1

Cat. No. 11-801 - Human Small Intestine Tissue Slide

Interferon-induced protein with tetratricopeptide repeats 1

Homo sapiens

Wathelet M, Moutschen S, Defilippi P, et al. Molecular cloning, full-length sequence and preliminary characterization of a 56-kDa protein induced by human interferons. Eur. J. Biochem. 1986; 155:11-7.

Fensterl V and Sen GC. The ISG56/IFIT1 gene family. J. Interferon Cytokine Res. 2011; 31:71-8.

Raychoudhuri A, Shrivastava S, Steele R, et al. ISG56 and IFITM1 proteins inhibit hepatitis C virus replication. J. Virol. 2011; 85:12881-9.

IFIT1 Antibody: C56, P56, G10P1, IFI56, ISG56, IFI-56, IFIT-1, IFNAI1, RNM561, IFI-56K, Interferon-induced protein with tetratricopeptide repeats 1, Interferon-induced 56 kDa protein

ELISA, WB, IHC-P, IF

116534937

Liquid