IFN beta (diervrij)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFN-α is an acid-stable molecule that signals through IFN-α/βR, which is also used by IFN-β. Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens. IFN-α contains four highly conserved cysteine residues that form two disulfide bonds, one of which is necessary for biological activity. Recombinant Human IFN-β is a 20.0 kDa protein containing 166 amino acid residues.
IFNB1; IFB; IFF; IFNB
3456
P01574
NP_002167.1
NM_002176
9p21
Human
Human, Mouse
MSYNLLGFLQ RSSNFQCQKL LWQLNGRLEY CLKDRMNFDI PEEIKQLQQF QKEDAALTIY EMLQNIFAIF RQDSSSTGWN ETIVENLLAN VYHQINHLKT VLEEKLEKED FTRGKLMSSL HLKRYYGRIL HYLKAKEYSH CAWTIVRVEI LRNFYFINRL TGYLRN
< 0.01 ng/µg of protein (< 0.1 EU/µg)
≥ 95% by SDS-PAGE gel and HPLC analyses.
Determined by its ability to stimulate the proliferation of human TF-1 cells. The expected ED50 is ≤ 0.25 ng/ml, corresponding to a specific activity of ≥ 4 x 106 units/mg.
166
Lyophilized
20 kDa
E. coli
Beschrijving
Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell proliferatio
Specificaties
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