IFNA1 Polyklonale Antilichaam

IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons (IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites or tumor cells. They belong to the large class of glycoproteins known as cytokines. IFNs stimulate the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs can activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes; and they also increase the ability of uninfected host cells to resist new infection by virus. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon is produced by mitogen- or antigen-stimulated T lymphocytes. IFNA1 is produced by macrophages and has antiviral activities.

IFN alpha; IFN-alpha-1; IFA1; Interferon alpha 1; IFNA1_MOUSE; IFNA11; IFNAB_MOUSE; IFN-alpha-11; Interferon alpha-11; Limitin; Q810G1_MOUSE; IFNA16; IFNA6T

15962

P01572

Mouse

121-189/189

IFNA1

Unconjugated

KLH conjugated synthetic peptide derived from mouse IFNA1

WB, IHC-P, IF (IHC-P)

Purified by Protein A.

1µg/µl

WB (1:300-5000), IHC-P (1:200-400), IF (IHC-P) (1:50-200)

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

The antibody targets Mouse IFNA1 protein, but will cross-react with IFNA11 and IFNA16

15962