IFNAR1 (NM 000629) Humaan Recombinant Proteïne

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor. [provided by RefSeq, Jul 2020]

Purified recombinant protein of Human interferon (alpha, beta and omega) receptor 1 (IFNAR1), Lys276-Asn416, with N-terminal His tag, expressed in E. coli, 50ug

AVP; IFN-alpha-REC; IFNAR; IFNBR; IFRC

3454

P17181

NM_000629

21q22.11

E. coli

N-His

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Toll-like receptor signaling pathway

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Toll-like receptor signaling pathway

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

50mM Tris, 8M Urea, pH8.0.

Druggable Genome, Transmembrane

16.3 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

IFNAR1

Human

NP_000620

https://www.ncbi.nlm.nih.gov/gene/3454

https://www.uniprot.org/uniprot/P17181

https://www.ncbi.nlm.nih.gov/nuccore/NM_000629

https://www.ncbi.nlm.nih.gov/nuccore/NP_000620