IGFALS Antilichaam - middengebied: Biotine (ARP42206 P050-Biotine)

Insulin-like growth factor binding protein, acid labile subunit

ALS, ACLSD

3483

P35858

NP_004961

Human, Mouse, Rat, Cow, Dog, Guinea Pig

The immunogen is a synthetic peptide directed towards the middle region of human IGFALS

IGFALS is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in IGFALS are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty.

PDCD6; IGF1; IGFBP5; IGFBP3

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 92%; Dog: 92%; Guinea Pig: 92%; Human: 100%; Mouse: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

63kDa

Heath, K.E., (2008) J. Clin. Endocrinol. Metab. 93 (5), 1616-1624

Wet Ice

605

IGFALS

IGFALS

Rabbit

Insulin-like growth factor-binding protein complex acid labile subunit

NM_004970

PGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEG