IGFBP3 (NM 001013398) Humaan Recombinant eiwit

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Purified recombinant protein of Human insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 1, Gly28-Lys297, with N-terminal His tag, expressed in E. coli, 50ug

BP-53; IBP3

3486

P17936

NM_001013398

7p12.3

E. coli

N-His

P53 signaling pathway

P53 signaling pathway

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

Druggable Genome, Secreted Protein

29.3 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

IGFBP3

Human

NP_001013416

https://www.ncbi.nlm.nih.gov/gene/3486

https://www.uniprot.org/uniprot/P17936

https://www.ncbi.nlm.nih.gov/nuccore/NM_001013398

https://www.ncbi.nlm.nih.gov/nuccore/NP_001013416