IGFBP5 / IGFBP-5 Proteïne (Zijn label)

Enables insulin-like growth factor I binding activity and receptor ligand activity. Involved in several processes, including cellular response to cAMP; regulation of smooth muscle cell migration; and regulation of smooth muscle cell proliferation. Part of insulin-like growth factor ternary complex. Biomarker of pulmonary fibrosis. [provided by Alliance of Genome Resources, Jun 2025]

IBP5 Protein

NP_000590.1

Human

Human

His-Tag

See Datasheet send with the product

< 1.0 EU per μg of the protein as determined by the LAL method

> 95 % as determined by SDS-PAGE.

Measured by its ability to inhibit the biological activity of IGF­I or IGF­II on MCF­7 human breast cancer cells. The ED50 for this effect is 0.1-0.5μg/mL in the presence of 14 ng/mL rhIGF­II.

263

Lyophilized

20 mM Tris, pH 8.0, 300 mM NaCl, 10 % glycerol.

See Datasheet

30 kDa

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Insect cells