IGSF8 Antilichaam - middengebied: Biotine (ARP59875 P050-Biotine)

Immunoglobulin superfamily, member 8

EWI2, PGRL, CD316, EWI-2, KCT-4, CD81P3, LIR-D1

93185

Q969P0

NP_443100

Human, Mouse, Cow, Dog, Guinea Pig, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human IGSF8

IGSF8 may play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. IGSF8 may also play a role on integrin-dependent morphology and motility functions. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.

KRTAP10-3; KRTAP10-8; KRTAP10-9; KRTAP10-7; KRTAP10-4; UBC; FBXO6; HIST1H2BK; TUBB6; TUBB7P; VPS35; TUBA8; EIF3L; TUBE1; RPL26L1; YBX2; EIF3K; LSM3; PDCD4; PABPC1; IBTK; RPL36; RPL13A; SF3B3; RPL35; SUPT16H; SRSF8; PRPF8; CCT4; ANP32B; DDX17; SYNCRIP; TUB

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 86%; Dog: 79%; Guinea Pig: 83%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

65kDa

Wet Ice

613

IGSF8

IGSF8

Rabbit

Immunoglobulin superfamily member 8

NM_052868

LAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEW