IKB alfa Antilichaam, KO gevalideerd

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

4792

P25963

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-317 of human IKB alpha (NP_065390.1) .

Unconjugated

Primary Antibodies

Antibody is Knockout validated.

Apoptosis, Cancer, Cell Cycle, Immunology, Innate Immunity, Signal Transduction, Transcription

Affinity purification

MCF-7

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 36kDa

IgG

NFKBIA

DU145

THP-1

A-549

Mouse spleen

Mouse thymus

Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

Homo sapiens

NFKBIA, IKBA, MAD-3, NFKBI

WB, IP

Liquid