IKZF2 Antilichaam

The Ikaros family zinc finger 2 (IKZF2) is a member of the Ikaros family of zinc-finger proteins, a family of hematopoietic-specific transcription factors involved in the regulation of lymphocyte development (1,2) . IKZF2 forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development (3) . Its expression is a marker for T cell activation and proliferation (4) .

22807

Q9UKS7

NP_057344

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Stem Cell, Immunology

IKZF2 antibody is affinity chromatography purified via peptide column.

Cat. No. 1287 - EL4 Cell Lysate

1 mg/mL

IKZF2 antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

IKZF2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

IKZF2 antibody is human, mouse and rat reactive. At least two isoforms of IKZF2 are known to exist; this antibody will detect both isoforms. IKZF2 antibody is predicted to not cross-react with other IKZF proteins.

IKZF2

Cat. No. 10-901 - Human Spleen Tissue Slide

Ikaros family zinc finger 2 (Helios)

Homo sapiens

Hahm K, Cobb BS, McCarty AS, et al. Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin. Genes Dev. 1998; 12:782-96.

John LB and Ward AC. The Ikaros gene family: transcriptional regulators of hematopoiesis and immunity. Mol. Immunol. 2011; 48:1272-8.

Kelly CM, Ikeda T, Koipally J, et al. Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors. Curr. Biol. 1998; 8:508-15.

Akimova T, Beier UH, Wang L, et al. Helios expression is a marker for T cell activation and proliferation. PLoS One 2011; 6:e24226.

Ikaros family zinc finger 2 (Helios), ANF1A2, HELIOS, ZNF1A2, ZNFN1A2

ELISA, WB, IHC-P, IF

119220596

Liquid