IL-12 Recombinant eiwit

IL-12 is a potent regulator of cell mediated immune responses and it induces IFN-gamma production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue type mast cells. Among its biological activities IL-12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells and induces the development of IFN-gamma producing Th1 cells. Recombinant murine IL-12 is a 75.0 kDa heterodimeric glycoprotein consisting of disulfide-linked 35 kDa (p35) and 40 kDa (p40) subunits (506 total amino acid residues) .

16159

P43431

NP_032377.1

Recombinant Proteins

CHO cells

Chemokines & Cytokines

Room Temp

The lyophilized IL-12 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IL-12 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IL-12 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Interleukin 12a

Mus musculus

P35, Ll12a, Il-12a, IL-12p35, Interleukin-12 subunit alpha, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL-12A

Murine

6680395

Lyophilized