IL-12/IL-23 p40 Antilichaam [C17,8]

The C17.8 antibody specifically reacts with the p40 subunit of IL-12, as free monomer, as a homodimer, or as a part of the p70 dimer. C17.8 seems to neutralize the activity of mouse IL-12 and IL-23. IL-12 is the p70 heterodimer of p35 and p40, expressed by the macrophages, dendritic cells, and monocytes. The C17.8 antibody cross-reacts with IL-23, since IL-23 also contains one p40 subunit.

16160

P43432

Mouse

C17.8

Unconjugated

Primary Antibodies

Innate Immunity

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Batch dependent

Phosphate-buffered aqueous solution, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C . Do not freeze.

Rat IgG2a, kappa

The C17.8 antibody specifically reacts with the p40 subunit of IL-12, as free monomer, as a homodimer, or as a part of the p70 dimer.

Il12b

Interleukin 12b

Mus musculus

P40, Il-12b, Il12p40, Il-12p40, Il12b

Flow, Functional Assays, IF, IP, WB, ELISA

Liquid