IL-13 Antilichaam

L13 inhibits proinflammatory cytokine production and stimulates antibody production. It induces proliferation in the human pre myeloid cell line TF1. IL13 has multiple effects on the differentiation and functions of monocytes and macrophages. It suppresses cytotoxic functions and induces changes in the morphology of human monocytes and in the phenotype of human monocytes and B cells by upregulating MHC class II expression. IL13 will also decrease the production of nitric oxide by activated murine macrophages, leading to impaired parasiticidal activity. Human and mouse interleukin 13 share approximately 58% amino acid sequence identity. Although human and mouse IL13 are equally active on human cells, human IL13 is much less active than mouse IL13 on mouse cells. Human IL13 and human IL4 also share approximately 30% sequence homology and have similar biological functions.

16163

P20109

P20109

Mouse

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant mIL-13 (murine Interleukin-13) .

Unconjugated

Primary Antibodies, Functional Antibodies, Antibody Pairs

Immunology, Chemokines & Cytokines

Anti-mIL-13 specific antibody was purified by affinity chromatography employing immobilized mIL-13 matrix.

Batch dependent

None

Room Temp

IL-13 antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

Il13

Interleukin 13

Mus musculus

Il-13, Il-13, Interleukin-13, T-cell activation protein P600, IL-13

ELISA, WB, Neutralization Assay

129377

Lyophilized