IL-17 Proteïne, Muis, Recombinant (His)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
>99%
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid sequence identity with human and rat IL-17A, respectively. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage. IL-17 is also able to increase bone destruction and reduce its formation. Blocking of interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation.
Ice Packs
-20°C
Beschrijving
IL-17 Proteïne, Muis, Recombinant (His) Beschikbaar in 5 µg. Bestel eenvoudig online met snelle levering.
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