IL-17A Recombinant eiwit

The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells. Recombinant human IL-17A is a 31.0 kDa disulfide-linked homodimer of two 136 amino acid polypeptide chains.

3605

Q16552

NP_002181.1

Recombinant Proteins

E. coli

Chemokines & Cytokines, Immunology, Innate Immunity, Signal Transduction

Room Temp

The lyophilized IL-17A recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IL-17A is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IL-17A recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Interleukin 17A

Homo sapiens

IL17, CTLA8, IL-17, IL-17A, IL17, Interleukin-17A, Cytotoxic T-lymphocyte-associated antigen 8

Human

4504651

Lyophilized