IL-1a Antilichaam [1F3B3]

Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

3552

P01583

P01583

Human

Ni-NTA purified recombinant human IL-1α expressed in E. Coli strain BL21 (DE3) .

1F3B3

Unconjugated

Primary Antibodies

Immunology, Innate Immunity, Neuroscience

Batch dependent

Ascitic fluid containing 0.03% sodium azide.

None

Blue Ice

IL-1a monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG2a

IL1A

Interleukin 1, alpha

Homo sapiens

Du, Y.; et al. 2000. Neurology 55: 480-484.

Grimaldi, L. et al. Ann. Neurol. 47: 361-365, 2000.

IL1F1, Hematopoietin-1, IL-1 alpha, IL1, IL-1A, IL1F1, IL1-ALPHA

ELISA, WB

124297