IL-1beta (menselijk) (Recombinant) (onder voorbehoud)

Source :E. coli Specific Binds to human IL-1R.IL-1beta is produced by activated macrophages. IL-1beta stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1beta belongs to the IL-1 family of proteins that are involved in the inflammatory response. IL-1beta in most situations requires the inflammasome complex to be cleaved and secreted.

Interleukin-1beta; IL-1F2

Human

Functional Assay

>=95% (SDS-PAGE)

Reconstitute with 100μl sterile water.0.1mg/mL after reconstitution. Lyophilized. Contains PBS.

Short Term Storage +4°C ; Long Term Storage-20°C ; After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0. 1% BSA should be used for further dilutions. Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

Biological Activity: Activates the NF-kB with an ED50 of <5ng/ml. Endotoxin Content <0.1EU/μg purified protein (LAL test; Lonza) .

Human IL-1beta (aa 117-269) is untagged.