IL-23 Recombinant eiwit

IL-23 is a proinflammatory heterodimeric protein composed of two subunits, a unique p19 subunit and a p40 subunit, which is shared with IL-12. IL-23 is secreted by activated dendritic cells and macrophages, and signals though a receptor comprised of IL-23R complexed with IL-12Rβ1. IL-23 has been shown to enhance proliferation of memory T cells. It also stimulates the production of IFN-gamma in NK cells, induces IL-17 production, and drives Th17 mediated responses. Recombinant IL-23 is a 53.5 kDa heterodimeric protein consisting of two subunits, p19 (170 amino acids) and p40 (306 amino acids) .*Manufactured using BTI-Tn-5B1-4 cells under license from the Boyce Thompson Institute for Plant Research, Inc.

51561

Q9NPF7

NP_057668.1

Recombinant Proteins

(BTI-Tn-5B1-4) High-5 Insect cells

Cancer, Chemokines & Cytokines, Immunology, Innate Immunity, Neuroscience

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Room Temp

The lyophilized IL-23 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IL-23 stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IL-23 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Interleukin 23, alpha subunit p19

Homo sapiens

P19, SGRF, IL-23, IL-23A, IL23P19, UNQ2498/PRO5798, Interleukin-23 subunit alpha, Interleukin-23 subunit p19, IL-23 subunit alpha

Human

7706702

Lyophilized