IL-31
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor) . GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant murine IL-31 is a 15.8 kDa protein containing 140 amino acid residues.
Il31; 1700013B14Rik
76399
Q6EAL8
NP_083870.1
NM_029594
5 F; 5
Mouse
Mouse
MTCSLSFGAP ISKEDLRTTI DLLKQESQDL YNNYSIKQAS GMSADESIQL PCFSLDREAL TNISVIIAHL EKVKVLSENT VDTSWVIRWL TNISCFNPLN LNISVPGNTD ESYDCKVFVL TVLKQFSNCM AELQAKDNTT C
< 0.1 ng/µg of protein (< 1EU/µg)
> 98% by SDS-PAGE & HPLC analyses
Testing in progress.
140
Lyophilized
15.8 kDa
E. coli
Beschrijving
IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals t
Specificaties
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