IL-36gamma Recombinant eiwit

The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36α (IL-1F6), β (IL-1F8) and γ (IL-1F9) . IL-36γ is highly expressed in psoriatic plaques and in tissues containing epithelial cells. IL-36γ signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36γ also functions as an agonist of NF-kappaB, and can stimulate the inflammatory response in bronchial epithelial cells. Recombinant human IL-36γ is a 17.0 kDa protein containing 152 amino acid residues.

56300

Q9NZH8

NP_001265497.1

Recombinant Proteins

E. coli

Immunology

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Room Temp

The lyophilized IL-36gama recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IL-36gama is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IL-36gama recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Interleukin 36, gamma

Homo sapiens

IL1E, IL1F9, IL1H1, IL-1F9, IL-1H1, IL1RP2, IL-1RP2, IL1E, UNQ2456/PRO5737, Interleukin-36 gamma, IL-1-related protein 2

Human

514388113

Lyophilized