IL-6 Antilichaam [2M8M3]

Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable) . The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable) .

3569

P05231

Virus

E. coli-derived human IL-6 protein, amino acids Pro29-Met212

2M8M3

Unconjugated

Primary Antibodies

Infectious Disease, COVID-19

Affinity Purified, Endotoxin Level: < 1.0 EU/ug of the protein by LAL method.

1mg/ml

Supplied as a 0.2um filtered solution in PBS, pH 7.4.

None

Blue Ice

This antibody can be stored at 2&#730; C to -8&#730; C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20&#730; C to -80&#730; C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Rabbit IgG

ELISA Capture: Recommended Concentration: 1-4ug/mL, Sample: Human IL-6 Monoclonal Antibody, Rabbit MAb (CAP) ELISA Detection: Recommended Concentration: 0.03-0.15ug/mL, Sample: Human IL-6 Monoclonal Antibody, Rabbit MAb (DET) Standard: Recommended Concentration: 0.78-50pg/mL, Sample: Recombinant Human IL6 Protein

IL6

Interleukin 6

Homo sapiens (human)

CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2

ELISA

74739144

Liquid