IL-6 Antilichaam (biotine)

IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages and endothelial cells. It acts upon a variety of cells including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. In addition, IL-6 appears to interact with IL2 in the proliferation of T lymphocytes. IL-6 potentiates the proliferative effect of IL-3 on multipotential hematopoietic progenitors. IL-6 is a multifunctional 24 kDa protein originally discovered in the medium of RNA stimulated fibroblastoid cells. It is upregulated by IL1, TNF, PDGF, IFN beta, TNF alpha, NGF, IL17 and downregulated by glucocorticoids IL4, TGF beta. IL-6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be as important as IL1 and TNF alpha in regulating the acute phase response. IL6 has also been implicated in regulating adipose mass.

24498

P20607

P20607

Rat

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant rat IL-6 (rat IL-6) .

Biotin

Primary Antibodies, Antibody Pairs

Immunology, Chemokines & Cytokines, Neuroscience

Anti-rat IL-6 specific antibody was purified by affinity chromatography and then biotinylated.

Batch dependent

None

Room Temp

IL-6 antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

Il6

Interleukin 6

Rattus norvegicustus norvegicus

ILg6, Ifnb2, Il-6, Interleukin-6IL-6

ELISA, WB

124350

Lyophilized