![IL-6 receptor Recombinant antilichaam [rhPM-1 (Tocilizumab) ] (OAAV00419)](/_ipx/q_80/productPlaceholder.webp)
IL-6 receptor Recombinant antilichaam [rhPM-1 (Tocilizumab) ] (OAAV00419)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Desmosome/hemidesmosome
Q8VE98
Human
F12 was established by fusing peripheral blood lymphocytes derived from a human vulgaris patient with a hetermyeloma cell line.
• Recombinant Monoclonal
F12
Recombinant Monoclonal Antibody
Purified
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
PBS with 0.02% Proclin 300.
Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
IgM, kappa
F12 recognizes an unknown polypeptide of desmosomal and hemidesmosomal plaques with a MW of 185 kDa (determined from immunoblotting using bovine tongue epithelium extract as the substrate), and by IEM (immunoelectron microscopy) it was determined that it is the intracellular part of the desmosome that is bound (Gilbert, 1997) . F12 shares some immunochemical properties with autoantibodies present in paraneoplastic pemphigus sera. Pemphigus diseases are those resulting in blistering of the skin due to the production of autoantibodies against keratinocyte surface proteins - autoantibodies of patients with pemphius vulgaris recognize desmoglein 1 (Dsg1), a major glycoprotein of the desmosome complex.
Human
Beschrijving
IL-6 receptor Recombinant antilichaam [rhPM-1 (Tocilizumab) ] (OAAV00419) Beschikbaar in 200 µg. Bestel eenvoudig online met snelle levering.
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