IL-9 Antilichaam

Interleukin 9 (IL-9) is a cytokine secreted by TH2 lymphocytes that acts as a regulator of a variety of hematopoietic cells, stimulates cell proliferation and prevents apoptosis (1,2) . It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins (3) . The IL-9 gene has been identified as a candidate gene for asthma (4) . Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness (5) .

3578

P15248

NP_000581

Human

7495

Unconjugated

Primary Antibodies

Recombinant Protein Test (Figure 2) : Anti-IL-9 antibodies (7495) detected human IL-9 recombinant protein at different concentrations. Recombinant Protein Test7495

Immunology

IL-9 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1306 - Human Spleen Tissue Lysate

1 mg/mL

IL-9 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

IL-9 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

IL-9 antibody is human specific. IL-9 antibody is predicted to no cross-react with IL-7.

Human IL-9 has one isoform (144aa, 16kD) . Mouse IL-9 has one isoform (144aa, 16kD) and Rat IL-9 also has one isoform (144aa, 16kD) . 7495 can detect human isoform, but cannot detect mouse and rat.

IL9

Cat. No. 10-901 - Human Spleen Tissue Slide

Cat. No. 1201 - HeLa Cell Lysate

Interleukin 9

Homo sapiens

Renauld et al. Cytokine 1990; 2:9-12.

Tete et al. J. Biol. Homeost. Agents 2012; 26:319-26.

Knoops and Renauld. Growth Factors 2004; 22:207-15.

Nicolaides et al. Proc. Natl. Acad. Sci. USA 1997; 94:13175-80.

IL-9 Antibody : P40, HP40, IL-9, Interleukin-9, Cytokine P40

ELISA, WB, IHC-P, IF

10834980

Liquid