IL12B Monoklonale Antilichaam

Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.1 PublicationAssociates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

IL12B

P43432

Mouse

Recombinant Mouse IL12B Protein

NKSF; IL-12/IL-23 p; IL-12 subunit p; NK cell stimulatory factor chain; NK cell Stimulating Factor Chain; CLMF; CLMF p; IL12 p; CLMF2; Cytotoxic lymphocyte maturation factor 40 kDa subunit; Cytotoxic Lymphocyte Maturation Factor 40 kDa subunit (CLMF p40) ; IL12; IL-12 p40; IL12 p70; IL-12 p70; IL-12/IL-23 p40; NK cell Stimulating Factor Chain 2; p40; IL-12B; NKSF2; Interleukin-12 subunit beta; CLMF p40; IL-12 subunit p40; NK cell stimulatory factor chain 2; IL 12B; Il12b

10A7

Unconjugated

IHC-P

Protein A

1 mg/mL

IHC-P 1:100-1:500

0.2 μm filtered solution in PBS

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/kj5k54Bt

IgG1