IL13 Antilichaam

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

3596

P35225

Human

A synthetic peptide of human IL13

Unconjugated

Primary Antibodies

Cancer, Chemokines & Cytokines, Immunology, Innate Immunity

Affinity purification

NCI-H460

Batch dependent

PBS with 0.02% sodium azide, pH7.3.

None

Blue Ice

Store at 4˚ C. Avoid freeze / thaw cycles.

Observed: 24kDa

IgG

IL13

Interleukin 13

Homo sapiens

IL13, Allergic rhinitis, ALRH, BHR1, Interleukin-13, NC30, p600, IL-13, Interleukin 13

WB, IHC, IF

Liquid