IL18BP Proteïne (C-human IgG1-Fc, menselijk)

IL18BP

FVH, IL18BPa

C-human IgG1-Fc

< 1.0 EU per μg protein as determined by the LAL method.

> 95 % as determined by SDS-PAGE.

1.Measured by its ability to inhibit the IL-18-induced response of KG‐1 human acute myelogenous leukemia cells. The ED50 for this effect is 0.1‐0.6 μg/mL in the presence of 50 ng/mL of recombinant human IL-18. 2.Recombinant Human IL-18BP Protein, hFc Tag (Cat. No. 10357-H02H) captured on Protein A chip can bind Recombinant Human IL-18 Protein (Cat. No. 10119-HNCE) with an affinity constant of 14.9 pM as determined in an SPR assay (Biacore 8K) (Routinely tested) . 3.Recombinant Human IL18BP Protein (Fc Tag) (Cat: 10357-H02H) captured on Protein A chip, can bind Recombinant Human IL18 / IL-18 Protein (Cat: 10119-HNCE) with an affinity constant of 59.650 pM as determined in an SPR assay (Biacore T200) (Routinely tested) .

Met1-Gly192

The recombinant human IL18BP consists of 402 amino acids and predicts a molecular mass of 44.4 kDa.

Human