IL1RL2 Antilichaam / Interleukine-1-receptor-achtige 2

IL1RL2, also known as interleukin-1 receptor-like 2, is a protein that belongs to the IL-1 receptor family. It is primarily expressed on the surface of immune cells, where it binds to specific ligands and triggers a cascade of signaling pathways that ultimately lead to the activation of immune responses. Studies have shown that IL1RL2 plays a critical role in the pathogenesis of various inflammatory diseases, such as asthma, rheumatoid arthritis, and inflammatory bowel disease. One of the key functions of IL1RL2 is its ability to regulate the production of pro-inflammatory cytokines, such as IL-6 and IL-8, which are responsible for promoting inflammation in the body. By modulating the activity of these cytokines, IL1RL2 helps to maintain the balance between pro-inflammatory and anti-inflammatory responses, thereby preventing excessive inflammation and tissue damage. Furthermore, IL1RL2 has also been shown to play a role in the activation of T cells and other immune cells, which are essential for mounting an effective immune response against pathogens.

Western blot: 1:2000-1:4000, Flow cytometry: 1:25 per million cells in 0.1ml

Q9HB29

Human

A portion of amino acids 257-286 from the human protein was used as the immunogen for this IL1RL2 antibody.

WB, FACS

Antigen affinity

Antigen affinity purified

This IL1RL2 antibody is available for research use only.

Store at 4°C for up to one month. For long term, aliquot the IL1RL2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

In 1X PBS, pH 7.4, with 0.09% sodium azide

The stated application concentrations are suggested starting amounts. Titration of the IL1RL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Flow cytometry testing of fixed human K562 cells with IL1RL2 antibody; Blue=isotype control, Green= IL1RL2 antibody.