IL24 Mouse Monoclonal Antibody [Kloon ID: LBI4E1]

This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) IL24 mouse monoclonal antibody, clone LBI4E1

C49A; FISP; IL10B; MDA7; MOB5; ST16

Homo sapiens interleukin 24 (IL24), transcript variant 1, mRNA.

11009

Q13007

Unconjugated

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

WB 1:500, IHC 1:150

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Secreted Protein

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

IL24

https://www.ncbi.nlm.nih.gov/gene/?term=11009

https://www.uniprot.org/uniprot/Q13007