IL28 Receptor alfa (IFNLR1) Mouse Monoclonal Antibody [Kloon ID: LBI3F5]

The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB) . The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29) . The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) IFNLR1 mouse monoclonal antibody, clone LBI3F5

CRF2/12; IFNLR; IL-28R1; IL28RA; LICR2

Homo sapiens interferon lambda receptor 1 (IFNLR1), transcript variant 1, mRNA.

163702

Q8IU57

Unconjugated

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

WB 1:500, IHC 1:500

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Transmembrane

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

IFNLR1

https://www.ncbi.nlm.nih.gov/gene/?term=163702

https://www.uniprot.org/uniprot/Q8IU57