IL4R & IL13RA1-eiwit (C-human IgG1-Fc, menselijk)

IL4R & IL13RA1

C-human IgG1-Fc

< 1.0 EU per μg protein as determined by the LAL method.

≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

1.Immobilized Recombinant Human IL-4Rα & IL-13Rα1 Heterodimer Protein (Fc Tag) (Cat: CT117-H02H) at 2 μg/mL (100 μL/well) can bind Recombinant Human IL-13 Protein (His Tag) (Cat: 10369-H08H), the EC50 is 15-45 ng/mL. 2.Loaded Recombinant Human IL-4Rα & IL-13Rα1 Heterodimer Protein, hFc Tag (Cat. No. CT117-H02H) on proA Biosensor, can bind Recombinant Human IL-13 Protein (Cat. No. 10369-HNAC) with an affinity constant of 1.690 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 3.Loaded Recombinant Human IL-4Rα & IL-13Rα1 Heterodimer Protein, hFc Tag (Cat. No. CT117-H02H) on proA Biosensor, can bind Recombinant Human IL-4 Protein (Cat. No. 11846-HNAE) with an affinity constant of 0.571 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) .

Met26-His232 & Gly22-Thr343

The recombinant heterodimer of Human IL-4Rα & IL-13Rα1 comprises 1033 (574+459) amino acids and has a calculated molecular mass of 115.2 (64.04+51.16) kDa. As a result of glycosylation, the apparent molecular mass of Human Integrin alpha V beta 8 heterodimer is approximately 69.2 kDa in SDS-PAGE under reducing conditions.

Human