IL7 Antilichaam

The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V (D) J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.

3574

P13232

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 26-177 of human IL7 (NP_000871.1) .

Unconjugated

Primary Antibodies

Apoptosis, Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology, Innate Immunity

Affinity purification

Mouse lung

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 33kDa

IgG

IL7

Mouse kidney

Mouse spleen

Rat kidney

Interleukin 7

Homo sapiens

IL-7Interleukin-7IL-7

WB, IHC, IF

Liquid