Ilaprazol (natrium) (standaard)

Ilaprazole (sodium) (Standard) is the analytical standard of Ilaprazole (sodium) . This product is intended for research and analytical applications. Ilaprazole (IY-81149) sodium is an orally active proton pump inhibitor. Ilaprazole sodium irreversibly inhibits H+/K+-ATPase in a dose-dependent manner with an IC50 of 6 μM in rabbit parietal cell preparation. Ilaprazole sodium is used for the research of gastric ulcers. Ilaprazole sodium is also a potent TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor[1][2].

172152-50-0

12352100

Proton Pump; Reference Standards; TOPK

Cell Cycle/DNA Damage; Membrane Transporter/Ion Channel; Others

Cancer; Inflammation/Immunology

O=S(C1=NC2=CC=C(N3C=CC=C3)C=C2[N-]1)CC4=NC=CC(OC)=C4C.[Na+]

C19H17N4NaO2S

388.42

[1]Kwon D, et al. Effects of IY-81149, a newly developed proton pump inhibitor, on gastric acid secretion in vitro and in vivo. Arzneimittelforschung. 2001;51 (3) :204-213.|[2]Zheng M, et al. Proton pump inhibitor ilaprazole suppresses cancer growth by targeting T-cell-originated protein kinase. Oncotarget. 2017;8 (24) :39143-39153.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-B2145R/

Reference Standards