Ilginatinibhydrochloride
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1239358-85-0
NS-018 hydrochloride
JAK
Angiogenesis
C21H20FN7.ClH
Ilginatinib hydrochloride (NS-018 hydrochloride) is a potent small-molecule inhibitor of JAK2 that is competitive with adenosine triphosphate (ATP) which exhibits 30–50-fold greater selectivity for JAK2 over other Jak-family kinases such as JAK1, JAK3, and TYK2.It inhibits JAK2, JAK1, JAK3, and TYK2 with IC50 of 0.72 nM, 33 nM, 39 nM, and 22 nM, respectively. It also showed potent inhibition of Src-family kinases, SRC and FYN. It can be used in research of myeloproliferative neoplasms.
Beschrijving
Ilginatinibhydrochloride Beschikbaar in 100 mg. Bestel eenvoudig online met snelle levering.
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