
Iloperidoncarbonzuur
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Iloperidone carboxylic acid (P95-12113) is the metabolite of Iloperidone. Iloperidone carboxylic acid exhibits good affinity for 5-HT2A receptor with pKi of 8.15, and moderate affinity for adrenergic receptor α1/α2B/α2C[1].
475110-48-6
P95-12113
12352005
5-HT Receptor; Adrenergic Receptor; Dopamine Receptor
GPCR/G Protein; Neuronal Signaling
Neuroscience-Neuromodulation
Neurological Disease
COC1=C(OCCCN2CCC(C3=NOC4=C3C=CC(F)=C4)CC2)C=CC(C(O)=O)=C1
C23H25FN2O5
428.45
[1]Subramanian N, et al., Receptor profile of P88-8991 and P95-12113, metabolites of the novel antipsychotic iloperidone. Prog Neuropsychopharmacol Biol Psychiatry. 2002 Apr;26 (3) :553-60.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W741575/
Reference compound1
No Development Reported
5-HT2 Receptor; D1 Receptor; D3 Receptor; MUC2; α adrenergic receptor; α-1 microglobulin
Beschrijving
Iloperidone carboxylic acid (P95-12113) is the metabolite of Iloperidone. Iloperidone carboxylic acid exhibits good affinity for 5-HT2A receptor with pKi of 8.1
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