IMPDH1 Antilichaam - middengebied: Biotine (ARP54363_P050-Biotine)

IMP (inosine 5'-monophosphate) dehydrogenase 1

IMPD, RP10, IMPD1, LCA11, IMPDH-I, sWSS2608

3614

P20839

NP_899066

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human IMPDH1

IMPDH1 acts as a homotetramer to regulate cell growth. It is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP) . This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10) .

UBC; LAMP2; IMPDH2; XRCC6; GMNN; HTRA1; DDX3X; SUMO4

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

IMPDH1 is supported by BioGPS gene expression data to be expressed in HeLa

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 79%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

62kDa

Wang, J., (2008) Clin. Pharmacol. Ther. 83 (5), 711-717

Wet Ice

563

IMPDH1

IMPDH1

Rabbit

Inosine-5'-monophosphate dehydrogenase 1

NM_183243

KKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRE