IMPDH2 Mouse Monoclonal Antibody [Kloon ID: LBI2F10]

This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) IMPDH2 mouse monoclonal antibody, clone LBI2F10

IMPD2; IMPDH-II

Homo sapiens inosine monophosphate dehydrogenase 2 (IMPDH2), mRNA.

3615

P12268

Unconjugated

Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism

Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism

WB 1:2000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

IMPDH2

https://www.ncbi.nlm.nih.gov/gene/?term=3615

https://www.uniprot.org/uniprot/P12268