
Inavolisib (GDC-0077)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2060571-02-8
RG6114, RO-7113755
C13576-5mg
PI3K
PI3K/Akt/mTOR
CC (C (=O) N) NC1=CC2=C (C=C1) C3=NC (=CN3CCO2) N4C (COC4=O) C (F) F
C18H19F2N5O4
Inavolisib (GDC-0077, RG6114, RO-7113755) is a potent selective inhibitor of PI3K alpha (PI3Kα) with an IC50 of 0.038 nM. GDC-0077 is >300-fold more selective for PI3K alpha over the other class I PI3K isoforms (beta, delta, and gamma) and >2000-fold more selective over PIK family members. GDC-0077 binds to the ATP binding site of PI3K and inhibits the phosphorylation of PIP2 to PIP3.
3 years -20°C powder
Beschrijving
Inavolisib (GDC-0077) Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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