Influenza A H3N2 Hemagglutinine antilichaam

Influenza A virus subtype H3N2, an enveloped virus of the Orthomyxoviridae family, is a respiratory infection in birds and mammals, and is an important cause of human influenza. In birds, humans, and pigs, the virus has mutated into many strains. Its derives from the forms of the two kinds of proteins on the surface of its coat, hemagglutinin (HA) and neuraminidase (NA) . Influenza A viruses are further classified into 16HA (H1-H16) and 9NA (N1-N9) serotypes based on the antigenic characteristics of HA and NA envelop glycoprotein. The extent of infection into host organisms are determined by HA, which interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues.

Hemagglutinin, Influenza A virus (A/Perth/16/2009 (H3N2) segment 4 hemagglutinin (HA) gene

Human

Influenza A

Recombinant Influenza A H3N2/HA1 (17-345aa) purified from Baculovirus

AT1B7

Unconjugated

ELISA, WB

By protein-G affinity chromatography

1 mg/mL (determined by BCA assay)

H3N2, HA, ATGA0535-10 µg, ATGA0535-20 µg, ATGA0535-50 µg, ATGA0535-100 µg, ATGA0535-250 µg, ATGA0535-500 µg, ATGA0535-1 mg, ATGA0535-10, ATGA0535-20, ATGA0535-50, ATGA0535-100, ATGA0535-250, ATGA0535-500, ATGA0535-1

Thomas H., et al. (2011) Ann N Y Acad Sci 1217: 178-190.; ; Wilson I.A., Cox N.J. (1990) Annu Rev Immunol 8: 737-771.; ; Cheng X., et al. (2012) Virology 432 (1) : 91-98.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Virus

ACS71642.1

C6KNH7

The recombinant proteins (100ng) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-Influenza A H3N2/HA antibody (1:1000) . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.; ; Lane 1.: Recombinant Influenza A H1N1/HA protein; ; Lane 2.: Recombinant Influenza A H5N2/HA protein; ; Lane 3.: Recombinant Influenza A H3N2/HA protein;