Influenza A virus Neuraminidase Recombinatie Proteïne

Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.

H8PF47

H8PF47_9INFA, GISAID

His Tag

Recombinant Proteins

HEK293 cells

Infectious Disease

>90% as determined by SDS-PAGE.

Supplied as 0.2 μm filtered solution in PBS, pH7.4, 300 mM NaCl with trehalose as protectant.

Dry Ice

Protein MUST be stored at -70˚ C or lower upon receipt. Avoid repeated freeze-thaw cycles.

The protein has a calculated MW of 53.2 kDa. The protein migrates as 65 kDa when calibrated against pre-stained protein marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

This recombinant protein can be used for WB. For research use only.

Manz B., et al., 2012, Submitted to the EMBL/GenBank/DDBJ databases.

NA, Neuraminidase

WB

Influenza A

Liquid