ING1 Antilichaam - C-terminalgebied: Biotine (ARP50512_T100-Biotine)

Inhibitor of growth family, member 1

P33, p47, p33ING1, p24ING1c, p33ING1b, p47ING1a

3621

Q5T9H0

NP_937862

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human ING1

ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of ING1 gene have been detected in various cancers.This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

SIRT1; SIRT2; UBC; HDAC1; KIAA0101; PCNA; RBP1; RBBP7; RBBP4; HDAC2; BRMS1L; SIN3A; BRMS1; SAP30; ELAVL1; SMURF1; COPS2; NQO1; HIST2H3C; MRGBP; YWHAZ; YWHAH; YWHAG; YWHAE; YWHAB; KPNA2; KPNB1; YWHAQ; SFN; ESR1; LMNA; CDKN2A; TP53; KAT2B; DMAP1; EP300; HHT

Biotin

Polyclonal Antibody

WB

There is BioGPS gene expression data showing that ING1 is expressed in HepG2

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 86%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

32kDa

Ahmed, I.A., (2008) Colorectal Dis 10 (4), 344-351

Wet Ice

279

ING1

ING1

Rabbit

Inhibitor of growth protein 1

NM_198219

EKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCD