Insulinereceptor alfa Recombinant antilichaam [83-7] (OAAV00138)

Interleukin 18

Iboctadekin; IFN-gamma-inducing factor; IGIF; IL-1 gamma; IL-18; IL1F4; IL-1g; Interferon gamma-inducing factor; interleukin 18 (interferon-gamma-inducing factor) ; interleukin-1 gamma; interleukin-18.

3606

P04637

NP_001230140.1

Human

Fusion of splenocytes from mice immunized with human IL-18, with SP2/O mouse myeloma cells.

125-2H

Recombinant Monoclonal Antibody

Purified

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

A proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable) . Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators (PubMed:14528293, PubMed:25500532) . Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells (Probable) (PubMed:10653850) .

PBS with 0.02% Proclin 300.

Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.

IgG1, kappa

Recognizes the active form of human IL-18.

IL18

Mouse

Interleukin-18

IL18

NM_001243211.1