INVS Antilichaam

This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

27130

Q9Y283

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human INVS (NP_055240.2) .

Unconjugated

Primary Antibodies

Cell Cycle, Neuroscience, Signal Transduction, Stem Cell

Affinity purification

293T

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 120kDa

IgG

WB: 1:500 - 1:2000

INVS

K-562

Mouse liver

Mouse kidney

Inversin

Homo sapiens

INV, NPH2, NPHP2, inversin, inversion of embryo turning homolog, inversion of embryonic turning, nephrocystin-2

WB

Liquid