INX-315
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2745060-92-6
C01910-5mg
CDK
Cell Cycle
INX-315 is an orally active and selective inhibitor of CDK2 that induces cell cycle arrest in the G1 phase. It exhibits an IC50 value of 2.3 nM in intracellular NanoBRET assay, respectively. It displays a 50-fold increased CDK2 selectivity compared to CDK1. INX-315 decreases the phosphorylation of CDK2 substrates and suppresses tumor growth in xenograft mouse models in a dose-dependent manner.
Beschrijving
INX-315 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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